{"id":5230,"date":"2023-05-26T11:48:01","date_gmt":"2023-05-26T09:48:01","guid":{"rendered":"https:\/\/www.abiogen.it\/bone-metabolism\/"},"modified":"2025-07-18T15:01:15","modified_gmt":"2025-07-18T13:01:15","slug":"bone-metabolism","status":"publish","type":"page","link":"https:\/\/www.abiogen.it\/en\/bone-metabolism\/","title":{"rendered":"Bone metabolism"},"content":{"rendered":"<section data-bb-version=\"4.5.6\" id=\"bt_bb_section69e03b32ec49f\" class=\"bt_bb_section bt_bb_layout_boxed_1200 bt_bb_vertical_align_top bt_bb_top_spacing_normal bt_bb_bottom_spacing_large\"  data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_normal&quot;,&quot;def&quot;:&quot;normal&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_large&quot;,&quot;def&quot;:&quot;large&quot;}}\"><div class=\"bt_bb_port\"><div class=\"bt_bb_cell\"><div class=\"bt_bb_cell_inner\"><div data-bb-version=\"4.6.1\" class=\"bt_bb_row \"  data-bt-override-class=\"{}\"><div class=\"bt_bb_row_holder\" ><div data-bb-version=\"4.6.1\"  class=\"bt_bb_column col-xxl-1 col-xl-1 col-xs-3 col-sm-3 col-md-3 col-lg-1 padding-right-0 bt_bb_vertical_align_top bt_bb_align_left bt_bb_padding_normal bt_bb_details-color_white\" style=\"; --column-width:1;\" data-width=\"1\" data-bt-override-class=\"{&quot;bt_bb_align_&quot;:{&quot;current_class&quot;:&quot;bt_bb_align_left&quot;,&quot;def&quot;:&quot;left&quot;},&quot;bt_bb_padding_&quot;:{&quot;current_class&quot;:&quot;bt_bb_padding_normal&quot;,&quot;def&quot;:&quot;normal&quot;}}\"><div class=\"bt_bb_column_content\"><div class=\"bt_bb_column_content_inner\"><div data-bb-version=\"4.5.9\" class=\"bt_bb_image ico-teraphy bt_bb_shape_square bt_bb_target_self bt_bb_align_inherit bt_bb_hover_style_simple bt_bb_content_display_always bt_bb_content_align_middle\" data-bt-override-class=\"{&quot;bt_bb_align_&quot;:{&quot;current_class&quot;:&quot;bt_bb_align_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;}}\"><span><img loading=\"lazy\" decoding=\"async\" width=\"100\" height=\"100\" src=\"https:\/\/www.abiogen.it\/wp-content\/uploads\/2023\/07\/metabolismo-osseo-ico-min.jpg\" class=\"attachment-full size-full\" alt=\"https:\/\/www.abiogen.it\/wp-content\/uploads\/2023\/07\/metabolismo-osseo-ico-min.jpg\" data-full_image_src=\"https:\/\/www.abiogen.it\/wp-content\/uploads\/2023\/07\/metabolismo-osseo-ico-min.jpg\" title=\"metabolismo-osseo-ico-min\" \/><\/span><\/div><\/div><\/div><\/div><div data-bb-version=\"4.6.1\"  class=\"bt_bb_column col-xxl-11 col-xl-11 col-xs-9 col-sm-9 col-md-9 col-lg-11 bt_bb_vertical_align_top bt_bb_align_left bt_bb_padding_normal\" style=\"; --column-width:11;\" data-width=\"11\" data-bt-override-class=\"{}\"><div class=\"bt_bb_column_content\"><div class=\"bt_bb_column_content_inner\"><header data-bb-version=\"4.6.1\" class=\"bt_bb_headline bt_bb_subheadline_text_transform_default bt_bb_dash_none bt_bb_size_inherit bt_bb_align_inherit\" data-bt-override-class=\"{&quot;bt_bb_size_&quot;:{&quot;current_class&quot;:&quot;bt_bb_size_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;},&quot;bt_bb_align_&quot;:{&quot;current_class&quot;:&quot;bt_bb_align_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;}}\"><h2 class=\"bt_bb_headline_tag\"><span class=\"bt_bb_headline_content\"><span>Abiogen Pharma: traditionally present in the \u201cbone metabolism\u201d market<\/span><\/span><\/h2><\/header><div data-bb-version=\"4.5.9\" class=\"bt_bb_separator bt_bb_border_style_none bt_bb_border_color_none bt_bb_top_spacing_none bt_bb_bottom_spacing_small\" data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_none&quot;,&quot;def&quot;:&quot;none&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_small&quot;,&quot;def&quot;:&quot;small&quot;}}\"><\/div><div data-bb-version=\"4.5.6\"  class=\"bt_bb_text\" ><\/p>\n<p>Abiogen Pharma is traditionally present in the \u201cBone Metabolism\u201d market thanks to the marketing of drugs, born and developed in its Research Centre and now distributed worldwide.<br \/>\nThis makes Abiogen Pharma an Italian excellence in this field and it is an important reference point in the national scientific landscape, thanks to its recognized leadership among different specialists.<\/p>\n<p>\n<\/div><div data-bb-version=\"4.5.9\" class=\"bt_bb_separator bt_bb_border_style_none bt_bb_border_color_none bt_bb_top_spacing_none bt_bb_bottom_spacing_normal\" data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_none&quot;,&quot;def&quot;:&quot;none&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_normal&quot;,&quot;def&quot;:&quot;normal&quot;}}\"><\/div><header data-bb-version=\"4.6.1\" class=\"bt_bb_headline bt_bb_subheadline_text_transform_default bt_bb_dash_none bt_bb_size_inherit bt_bb_align_inherit\" data-bt-override-class=\"{&quot;bt_bb_size_&quot;:{&quot;current_class&quot;:&quot;bt_bb_size_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;},&quot;bt_bb_align_&quot;:{&quot;current_class&quot;:&quot;bt_bb_align_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;}}\"><h2 class=\"bt_bb_headline_tag\"><span class=\"bt_bb_headline_content\"><span>Bone pathologies<\/span><\/span><\/h2><\/header><div data-bb-version=\"4.5.9\" class=\"bt_bb_separator bt_bb_border_style_none bt_bb_border_color_none bt_bb_top_spacing_none bt_bb_bottom_spacing_small\" data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_none&quot;,&quot;def&quot;:&quot;none&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_small&quot;,&quot;def&quot;:&quot;small&quot;}}\"><\/div><div data-bb-version=\"4.5.6\"  class=\"bt_bb_text\" ><\/p>\n<p>Abiogen Pharma commercializes therapies destined both for the treatment of more well-known pathologies such as <strong>osteoporosis, bone metastases, and osteolysis deriving from multiple myeloma<\/strong>, and for the treatment of rare pathologies such as the Paget syndrome, osteogenesis imperfecta, and <strong>algodystrophy<\/strong>, also known as <strong>Complex Regional Pain Syndrome<\/strong> (CRPS).<\/p>\n<p>\n<\/div><div data-bb-version=\"4.5.9\" class=\"bt_bb_separator bt_bb_border_style_none bt_bb_border_color_none bt_bb_top_spacing_none bt_bb_bottom_spacing_normal\" data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_none&quot;,&quot;def&quot;:&quot;none&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_normal&quot;,&quot;def&quot;:&quot;normal&quot;}}\"><\/div><header data-bb-version=\"4.6.1\" class=\"bt_bb_headline bt_bb_subheadline_text_transform_default bt_bb_dash_none bt_bb_size_inherit bt_bb_align_inherit\" data-bt-override-class=\"{&quot;bt_bb_size_&quot;:{&quot;current_class&quot;:&quot;bt_bb_size_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;},&quot;bt_bb_align_&quot;:{&quot;current_class&quot;:&quot;bt_bb_align_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;}}\"><h2 class=\"bt_bb_headline_tag\"><span class=\"bt_bb_headline_content\"><span>Osteoporosis: the most widespread pathology among bone diseases<\/span><\/span><\/h2><\/header><div data-bb-version=\"4.5.9\" class=\"bt_bb_separator bt_bb_border_style_none bt_bb_border_color_none bt_bb_top_spacing_none bt_bb_bottom_spacing_small\" data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_none&quot;,&quot;def&quot;:&quot;none&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_small&quot;,&quot;def&quot;:&quot;small&quot;}}\"><\/div><div data-bb-version=\"4.5.6\"  class=\"bt_bb_text\" ><\/p>\n<p><strong>Osteoporosis<\/strong> in particular, given its social relevance, is the most widespread pathology among bone diseases, especially owing to<strong> fragility fractures<\/strong>, which represent the most relevant clinical form. Even though osteoporotic fractures statistically affect above all post-menopausal women, there is now great awareness of the fact that fractures due to bone fragility are now an important problem also for men.<\/p>\n<p>\n<\/div><div data-bb-version=\"4.5.9\" class=\"bt_bb_separator bt_bb_border_style_none bt_bb_border_color_none bt_bb_top_spacing_none bt_bb_bottom_spacing_normal\" data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_none&quot;,&quot;def&quot;:&quot;none&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_normal&quot;,&quot;def&quot;:&quot;normal&quot;}}\"><\/div><header data-bb-version=\"4.6.1\" class=\"bt_bb_headline bt_bb_subheadline_text_transform_default bt_bb_dash_none bt_bb_size_inherit bt_bb_align_inherit\" data-bt-override-class=\"{&quot;bt_bb_size_&quot;:{&quot;current_class&quot;:&quot;bt_bb_size_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;},&quot;bt_bb_align_&quot;:{&quot;current_class&quot;:&quot;bt_bb_align_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;}}\"><h2 class=\"bt_bb_headline_tag\"><span class=\"bt_bb_headline_content\"><span>Algodystrophy or complex regional pain syndrome<\/span><\/span><\/h2><\/header><div data-bb-version=\"4.5.9\" class=\"bt_bb_separator bt_bb_border_style_none bt_bb_border_color_none bt_bb_top_spacing_none bt_bb_bottom_spacing_small\" data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_none&quot;,&quot;def&quot;:&quot;none&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_small&quot;,&quot;def&quot;:&quot;small&quot;}}\"><\/div><div data-bb-version=\"4.5.6\"  class=\"bt_bb_text\" ><\/p>\n<p><strong>Algodystrophy<\/strong> is a rare disease that manifests itself with pain often located in the limbs and resistant to common painkillers. In some cases, but not always, the onset is due to an injury or traumatic event, but the severity of the pain and the trend of the illness are out of proportion to the inciting event. The pain is normally associated with edema and a radiological test may highlight a localized osteoporosis that usually regresses with the regression of the illness. The disease is also known as Complex Regional Pain Syndrome (CRPS) of type 1 and 2.<\/p>\n<p>\n<\/div><div data-bb-version=\"4.5.9\" class=\"bt_bb_separator bt_bb_border_style_none bt_bb_border_color_none bt_bb_top_spacing_none bt_bb_bottom_spacing_normal\" data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_none&quot;,&quot;def&quot;:&quot;none&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_normal&quot;,&quot;def&quot;:&quot;normal&quot;}}\"><\/div><header data-bb-version=\"4.6.1\" class=\"bt_bb_headline bt_bb_subheadline_text_transform_default bt_bb_dash_none bt_bb_size_inherit bt_bb_align_inherit\" data-bt-override-class=\"{&quot;bt_bb_size_&quot;:{&quot;current_class&quot;:&quot;bt_bb_size_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;},&quot;bt_bb_align_&quot;:{&quot;current_class&quot;:&quot;bt_bb_align_inherit&quot;,&quot;def&quot;:&quot;inherit&quot;}}\"><h2 class=\"bt_bb_headline_tag\"><span class=\"bt_bb_headline_content\"><span>Osteogenesis imperfecta<\/span><\/span><\/h2><\/header><div data-bb-version=\"4.5.9\" class=\"bt_bb_separator bt_bb_border_style_none bt_bb_border_color_none bt_bb_top_spacing_none bt_bb_bottom_spacing_small\" data-bt-override-class=\"{&quot;bt_bb_top_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_top_spacing_none&quot;,&quot;def&quot;:&quot;none&quot;},&quot;bt_bb_bottom_spacing_&quot;:{&quot;current_class&quot;:&quot;bt_bb_bottom_spacing_small&quot;,&quot;def&quot;:&quot;small&quot;}}\"><\/div><div data-bb-version=\"4.5.6\"  class=\"bt_bb_text\" ><\/p>\n<p>Osteogenesis imperfecta is a group of hereditary disorders whose hallmarks are bone fragility and skeletal deformity. Other anomalies of the extraskeletal tissues, affecting teeth, skin, and ligaments, may add to these characteristics. The severity of osteogenesis imperfecta ranges from very mild to severe forms according to the bone and skeletal condition as well as to the other extra-skeletal manifestations.<\/p>\n<p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><!-- cell_inner --><\/div><!-- cell --><\/div><!-- port --><\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5230","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bone metabolism - Abiogen<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.abiogen.it\/en\/bone-metabolism\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bone metabolism - Abiogen\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.abiogen.it\/en\/bone-metabolism\/\" \/>\n<meta property=\"og:site_name\" content=\"Abiogen\" \/>\n<meta property=\"article:modified_time\" content=\"2025-07-18T13:01:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.abiogen.it\/wp-content\/uploads\/2023\/07\/logo-abiogen-social-min.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"765\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Bone metabolism - Abiogen","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.abiogen.it\/en\/bone-metabolism\/","og_locale":"en_US","og_type":"article","og_title":"Bone metabolism - Abiogen","og_url":"https:\/\/www.abiogen.it\/en\/bone-metabolism\/","og_site_name":"Abiogen","article_modified_time":"2025-07-18T13:01:15+00:00","og_image":[{"width":1200,"height":765,"url":"https:\/\/www.abiogen.it\/wp-content\/uploads\/2023\/07\/logo-abiogen-social-min.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.abiogen.it\/en\/bone-metabolism\/","url":"https:\/\/www.abiogen.it\/en\/bone-metabolism\/","name":"Bone metabolism - Abiogen","isPartOf":{"@id":"https:\/\/www.abiogen.it\/en\/#website"},"datePublished":"2023-05-26T09:48:01+00:00","dateModified":"2025-07-18T13:01:15+00:00","breadcrumb":{"@id":"https:\/\/www.abiogen.it\/en\/bone-metabolism\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.abiogen.it\/en\/bone-metabolism\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.abiogen.it\/en\/bone-metabolism\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.abiogen.it\/en\/"},{"@type":"ListItem","position":2,"name":"Bone metabolism"}]},{"@type":"WebSite","@id":"https:\/\/www.abiogen.it\/en\/#website","url":"https:\/\/www.abiogen.it\/en\/","name":"Abiogen","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.abiogen.it\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/www.abiogen.it\/en\/wp-json\/wp\/v2\/pages\/5230","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.abiogen.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.abiogen.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.abiogen.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.abiogen.it\/en\/wp-json\/wp\/v2\/comments?post=5230"}],"version-history":[{"count":6,"href":"https:\/\/www.abiogen.it\/en\/wp-json\/wp\/v2\/pages\/5230\/revisions"}],"predecessor-version":[{"id":16706,"href":"https:\/\/www.abiogen.it\/en\/wp-json\/wp\/v2\/pages\/5230\/revisions\/16706"}],"wp:attachment":[{"href":"https:\/\/www.abiogen.it\/en\/wp-json\/wp\/v2\/media?parent=5230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}