Equipment

Attrezzature Produttive per Sviluppo di Processo/prodotto e Studi Clinici

 

Equipment

Glove box (dedicated for API of clinical phase I-II)

Technology

Sampling and Dispensing

Capability / Typical range

 

Equipment

Turbola T2 mixer

Technology

Mixing

Capability / Typical range

from 1 up to 2 litres disposable containers

Equipment

Korsch XP1 R&D tablet press (single punch)

Technology

Tabletting

Capability / Typical range

Small product quantities (>10ml) Maximum press force 50 kN 3600 tablet/hour

Equipment

Multipharma MC-100 Semi-automatic capsule filling

Technology

Capsule Blinding studies

Capability / Typical range

3000 capsule/hour Hard gelatin and vegetal capsule 000-00-0-1-2-3-4-5-DB AA-A-B-C-D-E

Equipment

Twin-Pack Blistering machine O.M.A.R.

Technology

PVC/ALU PVC-PVDC/ALU

Capability / Typical range

7 cycles/minute

Equipment

CPE-6 electronic counting machine Multipharma

Technology

Count of capsules and tablets

Capability / Typical range

Capsules 00-1: 65.000 ora - Tablet diam. 14: 45.000 ora - Tablet diam. 6: 80.000 ora

Equipment

Silverson SL2 Homogeniser for liquids and suspensions

Technology

Liquid and Semi-solid (creams, gels, lotions and ointments)

Capability / Typical range

disposable containers

Equipment

Laminar Air Flow (dedicated for API of clinical phase III-IV)

Technology

Sampling and Dispensing

Capability / Typical range

 

Equipment

Multi Processor MP1 (laboratory fluid bed dryer) GEA Niro Pharma System

Technology

Mixing, Drying, agglomeration, top spray coating

Capability / Typical range

6 Kg – 8 Kg (16 litres capacity)

Equipment

PharmaConnect® (Through-the-Wall) GEA Niro Pharma System

Technology

 

Capability / Typical range

 

Equipment

High Shear Mixer

Technology

Granulation

Capability / Typical range

Develop. scale (3 litres Bowl size) 720 g -1.35 Kg - Pilot scale (30 litres Bowl size) 7.2 Kg – 13.5 Kg

Equipment

Lab Mini Blender Module

Technology

Mixing

Capability / Typical range

Bin 3 litres 450 g -1,2 Kg - Bin 5 litres 750 g -2,0 Kg - Bin 15 litres 2,25 Kg -6 Kg

Equipment

Thermotron T 7510 (Static Essiccator)

Technology

Drying

Capability / Typical range

 

Equipment

IMILL-F 5’’ Calibrating mill IMA

Technology

Calibration of wet or dry products

Capability / Typical range

Square holes (6-8-10 mm) Mainly used for wet granulation Round holes (0.35-6 mm) Mainly used for dry granulation

Equipment

Zanasi LAB 12 (Capsule filling machine) IMA

Technology

Powder, pellet, micro-tablets and liquid dosing into capsule

Capability / Typical range

12,000 capsules/hour Capsule size 5-000, DB, DB.AA

Equipment

Ronchi EA8 (High-speed rotary tablet presses)

Technology

Tabletting

Capability / Typical range

4,800-24,000 tablets/hour

Equipment

Kramer E80 (De-duster)

Technology

 

Capability / Typical range

 

Equipment

GS HTM/25 Tablet-coating equipment

Technology

Tablet coating

Capability / Typical range

25 litri

Equipment

Fantasy Plus (Primary packaging in blister) O.M.A.R.

Technology

PVC/ALU, PVC-PVDC/ALU PP/ALU, PP/PP PET/ALU, PVC-ACLAR/ALU ALU/ALU (ALU-OPA-PVC)

Capability / Typical range

4/8 cycles/minute

Equipment

Condor PPZ20 (homogeniser for liquids and suspensions)

Technology

Liquid and Semi-solid (creams, gels, lotions and ointments)

Capability / Typical range

20 litres

Equipment

Pompa peristaltica Watson&Marlow, mod. 520Di

Technology

Liquid and Semi-solid (creams, gels, lotions and ointments)liquidi e semisolidi (creme, geli, lozioni, unguenti)

Capability / Typical range

 

Principali Attrezzature Analitiche per Sviluppo/Convalida e Studi Clinici

Equipment

Perkin Elmer quaternary gradient HPLC system (UV, diode array and refractive index detectors)

Technology

HPLC

Capability

3 systems

Equipment

Shimadzu (LC-2010 CHT) quaternary gradient HPLC system (UV, diode array detector)

Technology

HPLC

Capability

1 system

Equipment

Dionex HPLC-IC system (Dionex ICS-3000)

Technology

HPLC-IC

Capability

1 system

Equipment

Water UPLC system (Water Acquity H-Class system)

Technology

UPLC

Capability

2 systems

Equipment

Perkin Elmer Pyris Hyper DSC

Technology

DSC

Capability

1 system

Equipment

Perkin Elmer 341 Polarimeter

Technology

Polarimeter

Capability

1 system

Equipment

Perkin Elmer Atomic absorption spectrometry AAS AA200

Technology

AAS

Capability

1 system

Equipment

Sotax automatic tester AT 7 smart

Technology

Dissolution

Capability

2 systems