Equipment
Attrezzature Produttive per Sviluppo di Processo/prodotto e Studi Clinici
Equipment
Glove box (dedicated for API of clinical phase I-II)
Technology
Sampling and Dispensing
Capability / Typical range
Equipment
Turbola T2 mixer
Technology
Mixing
Capability / Typical range
from 1 up to 2 litres disposable containers
Equipment
Korsch XP1 R&D tablet press (single punch)
Technology
Tabletting
Capability / Typical range
Small product quantities (>10ml) Maximum press force 50 kN 3600 tablet/hour
Equipment
Multipharma MC-100 Semi-automatic capsule filling
Technology
Capsule Blinding studies
Capability / Typical range
3000 capsule/hour Hard gelatin and vegetal capsule 000-00-0-1-2-3-4-5-DB AA-A-B-C-D-E
Equipment
Twin-Pack Blistering machine O.M.A.R.
Technology
PVC/ALU PVC-PVDC/ALU
Capability / Typical range
7 cycles/minute
Equipment
CPE-6 electronic counting machine Multipharma
Technology
Count of capsules and tablets
Capability / Typical range
Capsules 00-1: 65.000 ora - Tablet diam. 14: 45.000 ora - Tablet diam. 6: 80.000 ora
Equipment
Silverson SL2 Homogeniser for liquids and suspensions
Technology
Liquid and Semi-solid (creams, gels, lotions and ointments)
Capability / Typical range
disposable containers
Equipment
Laminar Air Flow (dedicated for API of clinical phase III-IV)
Technology
Sampling and Dispensing
Capability / Typical range
Equipment
Multi Processor MP1 (laboratory fluid bed dryer) GEA Niro Pharma System
Technology
Mixing, Drying, agglomeration, top spray coating
Capability / Typical range
6 Kg – 8 Kg (16 litres capacity)
Equipment
PharmaConnect® (Through-the-Wall) GEA Niro Pharma System
Technology
Capability / Typical range
Equipment
High Shear Mixer
Technology
Granulation
Capability / Typical range
Develop. scale (3 litres Bowl size) 720 g -1.35 Kg - Pilot scale (30 litres Bowl size) 7.2 Kg – 13.5 Kg
Equipment
Lab Mini Blender Module
Technology
Mixing
Capability / Typical range
Bin 3 litres 450 g -1,2 Kg - Bin 5 litres 750 g -2,0 Kg - Bin 15 litres 2,25 Kg -6 Kg
Equipment
Thermotron T 7510 (Static Essiccator)
Technology
Drying
Capability / Typical range
Equipment
IMILL-F 5’’ Calibrating mill IMA
Technology
Calibration of wet or dry products
Capability / Typical range
Square holes (6-8-10 mm) Mainly used for wet granulation Round holes (0.35-6 mm) Mainly used for dry granulation
Equipment
Zanasi LAB 12 (Capsule filling machine) IMA
Technology
Powder, pellet, micro-tablets and liquid dosing into capsule
Capability / Typical range
12,000 capsules/hour Capsule size 5-000, DB, DB.AA
Equipment
Ronchi EA8 (High-speed rotary tablet presses)
Technology
Tabletting
Capability / Typical range
4,800-24,000 tablets/hour
Equipment
Kramer E80 (De-duster)
Technology
Capability / Typical range
Equipment
GS HTM/25 Tablet-coating equipment
Technology
Tablet coating
Capability / Typical range
25 litri
Equipment
Fantasy Plus (Primary packaging in blister) O.M.A.R.
Technology
PVC/ALU, PVC-PVDC/ALU PP/ALU, PP/PP PET/ALU, PVC-ACLAR/ALU ALU/ALU (ALU-OPA-PVC)
Capability / Typical range
4/8 cycles/minute
Equipment
Condor PPZ20 (homogeniser for liquids and suspensions)
Technology
Liquid and Semi-solid (creams, gels, lotions and ointments)
Capability / Typical range
20 litres
Equipment
Pompa peristaltica Watson&Marlow, mod. 520Di
Technology
Liquid and Semi-solid (creams, gels, lotions and ointments)liquidi e semisolidi (creme, geli, lozioni, unguenti)
Capability / Typical range
Principali Attrezzature Analitiche per Sviluppo/Convalida e Studi Clinici
Equipment
Perkin Elmer quaternary gradient HPLC system (UV, diode array and refractive index detectors)
Technology
HPLC
Capability
3 systems
Equipment
Shimadzu (LC-2010 CHT) quaternary gradient HPLC system (UV, diode array detector)
Technology
HPLC
Capability
1 system
Equipment
Dionex HPLC-IC system (Dionex ICS-3000)
Technology
HPLC-IC
Capability
1 system
Equipment
Water UPLC system (Water Acquity H-Class system)
Technology
UPLC
Capability
2 systems
Equipment
Perkin Elmer Pyris Hyper DSC
Technology
DSC
Capability
1 system
Equipment
Perkin Elmer 341 Polarimeter
Technology
Polarimeter
Capability
1 system
Equipment
Perkin Elmer Atomic absorption spectrometry AAS AA200
Technology
AAS
Capability
1 system
Equipment
Sotax automatic tester AT 7 smart
Technology
Dissolution
Capability
2 systems